Which Airbus aircraft holds the distinction of being the world's first twin-engine wide-body airliner?

The distinction of being the world's first twin-engine wide-body airliner belongs to the A300. Introduced in the early 1970s, the Airbus A300 was a groundbreaking aircraft that set new standards in commercial aviation. Its design featured two engines, which were a departure from the traditional quad-engine configurations that were common at the time for wide-body aircraft. This innovation not only improved fuel efficiency but also reduced operational costs for airlines. The A300 paved the way for future designs in the aviation industry, influencing the development of subsequent aircraft models not just from Airbus but also from other manufacturers.

The other aircraft options do not fit this description as they were either developed after the A300 or do not hold the same historical significance in terms of being the first in their category. For instance, the A310 is a derivative of the A300 and introduced later, while the A320 is a narrow-body aircraft and does not qualify as a wide-body. The A330, while also a twin-engine wide-body, was developed much later and therefore cannot claim the title of the first in this category.